Apixaban for Extended Anticoagulation (APIDULCIS)
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- STATUS
- Recruiting
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- End date
- Jan 23, 2023
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- participants needed
- 1200
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- sponsor
- Arianna Anticoagulazione Foundation
Summary
The study aims at optimizing the long-term and extended management of patients with a first episode of venous thromboembolism (proximal deep vein thrombosis with or without pulmonary embolism) (VTE). Patients at high risk of recurrence (with altered D-dimer test), who had received anticoagulation (whatever the drug used) for 12-15 months after the first episode of thrombosis, will be treated with Apixaban 2,5 mg x 2 for 18 months as extended treatment. Patients at low risk, with normal D-dimer test, will stop anticoagulation definitely.
Description
This prospective cohort study aims to assess the efficacy and safety of a management procedure to decide on giving or not an extended anticoagulation (administering apixaban 2 2.5 mg twice daily ) to outpatients with a single episode of proximal deep vein thrombosis of the lower limbs and/or pulmonary embolism who had received 12-15 months of anticoagulation (whatever the anticoagulant drug used). The study seeks to assess whether a management procedure involving D-dimer testing assessment can identify a subset of subjects at low risk of recurrence in whom an extended anticoagulation can be safely avoided.
Details
| Condition | Venous Thromboembolism, Anticoagulants, Thromboembolism, anticoagulant, blood thinner, agents, anticoagulant, anticoagulation agents, blood thinners, anticoagulant drugs |
|---|---|
| Treatment | Apixaban |
| Clinical Study Identifier | NCT03678506 |
| Sponsor | Arianna Anticoagulazione Foundation |
| Last Modified on | 23 January 2021 |
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