Last updated on February 2019

A Phase III Study to Evaluate the Port Delivery System Implant With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration (Archway)


Brief description of study

Study GR40548 is a Phase III, randomized, multicenter, open-label (visual assessor [VA]-masked), active-comparator study designed to assess the efficacy, safety, and pharmacokinetics (PK) of 100mg/ml delivered via the Port Delivery System (PDS) compared with ranibizumab intravitreal injections at 0.5 mg (10 mg/mL) in participants with neovascular age-related macular degeneration (nAMD).

Clinical Study Identifier: NCT03677934

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Reference Study ID Number: GR40548 ...

Retinal Consultants of Arizona
Phoenix, AZ United States
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Reference Study ID Number: GR40548 ...

Barnet Dulaney Perkins Eye Center
Phoenix, AZ United States
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Reference Study ID Number: GR40548 ...

Associated Retina Consultants
Phoenix, AZ United States
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Reference Study ID Number: GR40548 ...

Arizona Retina and Vitreous Consultants
Phoenix, AZ United States
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Reference Study ID Number: GR40548 ...

California Retina Consultants
Bakersfield, CA United States
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Reference Study ID Number: GR40548 ...

Retina-Vitreous Associates Medical Group
Beverly Hills, CA United States
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Reference Study ID Number: GR40548 ...

The Retina Partners
Encino, CA United States
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Reference Study ID Number: GR40548 ...

Retina Consultants of Orange County
Fullerton, CA United States
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Reference Study ID Number: GR40548 ...

Jacobs Retina center at the Shiley eye Institute UCSD
La Jolla, CA United States
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Reference Study ID Number: GR40548 ...

Jules Stein Eye Institute/ UCLA
Los Angeles, CA United States
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Reference Study ID Number: GR40548 ...

N CA Retina Vitreous Assoc
Mountain View, CA United States
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Reference Study ID Number: GR40548 ...

Byers Eye Insitute at Stanford
Palo Alto, CA United States
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Reference Study ID Number: GR40548 ...

Retina Consultants, San Diego
Poway, CA United States
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Reference Study ID Number: GR40548 ...

Retina Consultants of Southern California
Redlands, CA United States
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Reference Study ID Number: GR40548 ...

Retinal Consultants Med Group
Sacramento, CA United States
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Reference Study ID Number: GR40548 ...

West Coast Retina Medical Group
San Francisco, CA United States
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Reference Study ID Number: GR40548 ...

UCSF; Ophthalmology
San Francisco, CA United States
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Reference Study ID Number: GR40548 ...

Orange County Retina Med Group
Santa Ana, CA United States
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Reference Study ID Number: GR40548 ...

California Retina Consultants
Santa Barbara, CA United States
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Reference Study ID Number: GR40548 ...

Bay Area Retina Associates
Walnut Creek, CA United States
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Reference Study ID Number: GR40548 ...

Southwest Retina Consultants
Durango, CO United States
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Reference Study ID Number: GR40548 ...

Eye Center of Northern CO
Fort Collins, CO United States
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Colorado Retina Associates, PC
Golden, CO United States
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Reference Study ID Number: GR40548 ...

Retina Group of New England
New London, CT United States
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Reference Study ID Number: GR40548 ...

Retina Health Center
Fort Myers, FL United States
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National Ophthalmic Research Institute
Fort Myers, FL United States
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Reference Study ID Number: GR40548 ...

Florida Eye Associates
Melbourne, FL United States
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Reference Study ID Number: GR40548 ...

Retina Care Specialists
Palm Beach Gardens, FL United States
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Reference Study ID Number: GR40548 ...

Retina Specialty Institute
Pensacola, FL United States
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Reference Study ID Number: GR40548 ...

Fort Lauderdale Eye Institute
Plantation, FL United States
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Reference Study ID Number: GR40548 ...

Retina Vitreous Assoc of FL
Saint Petersburg, FL United States
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Reference Study ID Number: GR40548 ...

Southern Vitreoretinal Assoc
Tallahassee, FL United States
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Reference Study ID Number: GR40548 ...

Retina Associates of Florida, LLC
Tampa, FL United States
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Southeast Retina Center
Augusta, GA United States
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Georgia Retina PC
Marietta, GA United States
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Reference Study ID Number: GR40548 ...

University of Illinois at Chicago College of Medicine; Illilnois Eye and Ear Infirmary
Chicago, IL United States
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Illinois Retina Associates
Joliet, IL United States
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Reference Study ID Number: GR40548 ...

University Retina and Macula Associates, PC
Oak Forest, IL United States
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Reference Study ID Number: GR40548 ...

Wolfe Eye Clinic
West Des Moines, IA United States
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Retina Associates
Shawnee Mission, KS United States
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Retina Associates of Kentucky
Lexington, KY United States
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Paducah Retinal Center
Paducah, KY United States
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Maine Eye Center
Portland, ME United States
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The Retina Care Center
Baltimore, MD United States
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Reference Study ID Number: GR40548 ...

Johns Hopkins Med; Wilmer Eye Inst
Baltimore, MD United States
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Retina Group of Washington
Chevy Chase, MD United States
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Retina Specialists
Towson, MD United States
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Tufts Medical Center
Boston, MA United States
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Ophthalmic Consultants of Boston
Boston, MA United States
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Reference Study ID Number: GR40548 ...

Vitreo-Retinal Associates, PC
Worcester, MA United States
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Reference Study ID Number: GR40548 ...

Associated Retinal Consultants
Grand Rapids, MI United States
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Foundation for Vision Research
Grand Rapids, MI United States
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Reference Study ID Number: GR40548 ...

Vitreoretinal Surgery
Edina, MN United States
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University of Minnesota
Minneapolis, MN United States
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Midwest Vision Research Foundation
Chesterfield, MO United States
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The Retina Institute - Chesterfield
Chesterfield, MO United States
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Reference Study ID Number: GR40548 ...

Sierra Eye Associates
Reno, NV United States
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Reference Study ID Number: GR40548 ...

Retina Center of New Jersey
Bloomfield, NJ United States
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Mid Atlantic Retina - Wills Eye Hospital
Cherry Hill, NJ United States
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Retina Associates of NJ
Teaneck, NJ United States
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Reference Study ID Number: GR40548 ...

University of New Mexico; School of Med
Albuquerque, NM United States
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Reference Study ID Number: GR40548 ...

Long Is. Vitreoretinal Consult
Hauppauge, NY United States
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Reference Study ID Number: GR40548 ...

Vitreous-Retina-Macula
New York, NY United States
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Reference Study ID Number: GR40548 ...

Ophthalmic Consultants of Long Island
Rockville Centre, NY United States
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Reference Study ID Number: GR40548 ...

The Retina Consultants
Slingerlands, NY United States
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Retina Vit Surgeons/Central NY
Syracuse, NY United States
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Reference Study ID Number: GR40548 ...

Char Eye Ear &Throat Assoc
Charlotte, NC United States
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Reference Study ID Number: GR40548 ...

Cincinnati Eye Institute
Cincinnati, OH United States
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Reference Study ID Number: GR40548 ...

The Cleveland Clinic Foundation
Cleveland, OH United States
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Reference Study ID Number: GR40548 ...

OSU Eye Physicians & Surgeons
Columbus, OH United States
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Retina Vitreous Center
Edmond, OK United States
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Retina Northwest
Portland, OR United States
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Oregon HSU; Casey Eye Institute
Portland, OR United States
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Palmetto Retina Center
Florence, SC United States
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Charles Retina Institution
Germantown, TN United States
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Tennessee Retina PC
Nashville, TN United States
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Texas Retina Associates
Arlington, TX United States
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Reference Study ID Number: GR40548 ...

Austin Retina Associates
Austin, TX United States
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Reference Study ID Number: GR40548 ...

Retina Research Center
Austin, TX United States
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Reference Study ID Number: GR40548 ...

Texas Retina Associates
Fort Worth, TX United States
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Reference Study ID Number: GR40548 ...

Retina Consultants of Houston
Houston, TX United States
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Reference Study ID Number: GR40548 ...

Valley Retina Institute P.A.
McAllen, TX United States
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Reference Study ID Number: GR40548 ...

Med Center Ophthalmology Assoc
San Antonio, TX United States
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Reference Study ID Number: GR40548 ...

Retina Consultants of Houston
The Woodlands, TX United States
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Reference Study ID Number: GR40548 ...

Retina Associates of Utah
Salt Lake City, UT United States
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Reference Study ID Number: GR40548 ...

Rocky Mountain Retina
Salt Lake City, UT United States
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Reference Study ID Number: GR40548 ...

Wagner Macula & Retina Center
Norfolk, VA United States
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Reference Study ID Number: GR40548 ...

Retina Institute of Virginia
Richmond, VA United States
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Reference Study ID Number: GR40548 ...

Retina Center Northwest
Silverdale, WA United States
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Reference Study ID Number: GR40548 ...

Spokane Eye Clinical Research
Spokane, WA United States
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Recruitment Status: Open


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