The Efficacy Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel

  • STATUS
    Not Recruiting
  • participants needed
    360
  • sponsor
    Jiangsu vcare pharmaceutical technology co., LTD
Updated on 23 January 2021
heart disease
clopidogrel
percutaneous coronary intervention
antiplatelet therapy

Summary

This is a multi-center, randomized, double-blind, triple-dummy, parallel-controled, dose-exploration phase II trial. Patients with coronary atherosclerotic heart disease and planned percutaneous coronary intervention PCI will be randomized after informed consent, in a 1:1:1:1 ratio to the following treatment groups: Experimental group 1 : Vicagrel 20mg loading followed by 5mg/day for 28 days; Experimental group 2 : Vicagrel 24mg loading followed by 6mg/day for 28 days; Experimental group 3 : Vicagrel 30mg loading followed by 7.5mg/day for 28 days; Control group : Clopidogrel 300mg loading followed by 75mg/day for 28 days. The primary purpose of this trial is to evaluate the efficacy, safety of vicagrel antiplatelet therapy and explore dose in patients with coronary atherosclerotic heart disease during and after PCI compared with clopidogrel.

Details
Condition Coronary Artery Disease, Coronary heart disease, Platelet Aggregation Inhibitors, Percutaneous Coronary Intervention
Treatment Clopidogrel 75mg, Vicagrel 5mg, Vicagrel 6mg, Vicagrel 7.5mg
Clinical Study IdentifierNCT03599284
SponsorJiangsu vcare pharmaceutical technology co., LTD
Last Modified on23 January 2021

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note