Last updated on September 2018

Ilaris (Canakinumab) in Patient With Periodic Fever Aphthous Stomatitis Pharyngitis and Cervical Adenitis (PFAPA)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Familial Mediterranean Fever
  • Age: Between 2 - 10 Years
  • Gender: Male or Female

Key inclusion criteria

  1. Patients in ages 2-10 years old who are diagnosed with PFAPA at least 3 months prior to enrollment according to clinical criteria will be screened for this study.
  2. Suffer from more than 4 PFAPA flares 2 months prior to the screening period.
  3. Have signed informed consent for the study.
  4. Have at least 2 documented PFAPA flare during the screening period.

Key exclusion criteria

  1. Patients who are diagnosed with chronic disease including another auto inflammatory disease.
  2. Patients who suffer from neutropenia or elevated liver enzymes.
  3. Patients who receive treatment with cimetidine/famotidine, montelukast or colchicine 2 weeks or less prior to enrollment.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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