Registry on the EXperience of Extracorporeal CO2 Removal in Intensive Care Units

  • STATUS
    Recruiting
  • End date
    Jun 25, 2022
  • participants needed
    200
  • sponsor
    Rexecor
Updated on 25 January 2021

Summary

Investigators will aim to conduct an observational study in order to assess very thoroughly all patients implanted by Extracorporeal carbon dioxide removal (ECCO2R) in 10 critical care units of Paris and its surburb (APHP, Assistance Publique des hpitaux de Paris).

Secondary objectives will be:

  1. to assess efficacy and safety of ECCO2R,
  2. to compare the data issue from the registry to others studies assessing the same population and to other centers and
  3. to compare the different ECCOR devices in terms of efficacy and adverse events.

Description

The registry will be conducted prospectively during 2 years in 10 ICUs of l'APHP on behalf on the CEDIT. The 10 centers are : (1) ICU of l'hpital europen Georges Pompidou, (2) ICU of l'Hpital Louis Mourier, (3) ICU of l'Hpital de Bictre, (4) ICU of GHPS, (5) Respiratory ICU of GHPS, (6) ICU of l'Hpital Lariboisire (7) ICU of l'Hpital Cochin (8) ICU of l'Hpital Saint-Antoine (9)ICU of l'Hpital Henri Mondor and (10) ICU of l'Hpital Tenon.

The primary outcome will be the number of patients implanted by ECCO2R monthly in each center during the 2 years period study.

Secondary outcomes will be ICU-mortality, invasive ventilation duration, non invasive ventilation duration, ICU duration, modalities of ventilation at the ICU discharge, hemorragic complications due to the ECCOR device, thrombotic complications due to ECCO2R device, intravascular hemolysis due to ECCO2R device, duration of ECCO2R, adjunct therapy to ECCO2R and reasons of ECCO2R discontinuation.

Details
Condition Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Patients With Acute Respiratory Distress Syndrome
Treatment ECCO2R
Clinical Study IdentifierNCT02965079
SponsorRexecor
Last Modified on25 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Gender: Male or Female
Do you have any of these conditions: Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease or Patients With Acute Respiratory Distress Syndrome?
Patients implanted with ECCCO2R

Exclusion Criteria

Contra-indication to ECCO2R
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