Last updated on April 2019

INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists Rivaroxaban or Aspirin Studies Non-Inferiority


Brief description of study

This program is a comprehensive evaluation of rheumatic valvular heart disease (RVHD), Atrial fibrillation (AF)/flutter and stroke.

A prospective, randomized, parallel group, open-label clinical trial of rivaroxaban versus standard vitamin K antagonists (VKA) therapy to evaluate non-inferiority of rivaroxaban to VKA, with testing for superiority if non-inferiority is satisfied.

Clinical Study Identifier: NCT02832544

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Cl nica Procardio Ltda.

Blumenau, Brazil
0.81miles
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