Last updated on January 2019

PRospective Prostate biOmarker Study


Brief description of study

Correlation of a glycoprotein panel with prostate biopsy outcome and PCa aggressiveness

Detailed Study Description

The main objective of this study is to correlate a glycoprotein panel with prostate biopsy outcome, i.e. distinguishing PCa from benign prostatic conditions as well as high-grade cancer. The quantities of the two protein analytes cathepsin D (CTSD) and thrombospondin 1 (THBS1) are measured in human serum samples. In combination with percent free PSA (%fPSA), the results are correlated with prostate biopsy outcome. The potential future benefit of using this glycoprotein panel is to validate positive tPSA tests in men with negative digital rectal examination (DRE) and enlarged prostates to reduce the need for undergoing a biopsy, thereby reducing unnecessary biopsies and potentially predicting high-grade disease.

Clinical Study Identifier: NCT03565289

Contact Investigators or Research Sites near you

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Andreas Roder, Dr.

Rigshospitalet
Copenhagen, Denmark
1.73miles
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Recruitment Status: Open


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