A Study of Nivolumab In Combination With Cabozantinib in Patients With Non-Clear Cell Renal Cell Carcinoma

  • End date
    Aug 16, 2023
  • participants needed
  • sponsor
    Memorial Sloan Kettering Cancer Center
Updated on 7 October 2022
platelet count
measurable disease
serum bilirubin
primary tumor
bone metastases
ovarian suppression
kidney cancer
metastatic renal cell carcinoma
clear cell renal cell carcinoma


The purpose of this study is to compare any good and bad effects of using a combination of nivolumab (Opdivo®) and cabozantinib (Cabometyx®) in people with metastatic kidney cancer.

Condition Advanced or Metastatic Non-clear Cell Renal Cell Carcinoma, Unclassified Renal Cell Carcinoma, Papillary Renal Cell Carcinoma, Fumarate Hydratase Deficient Renal Cell Carcinoma, Succinate Dehydrogenase Deficient Renal Cell Carcinoma, Collecting Duct Renal Cell Carcinoma, Chromophobe Renal Cell Carcinoma
Treatment Nivolumab, Cabozantinib
Clinical Study IdentifierNCT03635892
SponsorMemorial Sloan Kettering Cancer Center
Last Modified on7 October 2022


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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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