Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection

  • End date
    Apr 24, 2024
  • participants needed
  • sponsor
    Centre Hospitalier Intercommunal Creteil
Updated on 24 January 2021
premature birth
perinatal morbidity
fetal growth retardation
toxemia of pregnancy


Preeclampsia and intrauterine growth retardation (IUGR) are serious and frequent pathologies, specific to pregnancy. They represent 70 000 new cases a year, or 9% of pregnancies and cause 50,000 premature births per year in France. The consequences in terms of morbidity and perinatal morbidity and the medical and economic costs make it an issue public health. Pre-eclampsia associates maternal hypertension with dysfunction kidney. There is no cure for pre-eclampsia or IUGR vascular during pregnancy. These pathologies invariably evolve towards a maternal and / or fetal aggravation sometimes very fast. Primary prevention and secondary education and screening for these pathologies are still insufficient. A better understanding of the pathophysiology of these placental vascular pathologies is necessary for the development of supported medical, obstetric and pediatric that will improve the state of health maternal and neonatal

Condition Pre-Eclampsia, Preeclampsia, toxemia of pregnancy
Treatment collect of placenta, blood and urinary samples at delivery
Clinical Study IdentifierNCT03626233
SponsorCentre Hospitalier Intercommunal Creteil
Last Modified on24 January 2021


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Inclusion Criteria

Is your age greater than or equal to 18 yrs?
Are you female?
Do you have any of these conditions: Pre-Eclampsia or Preeclampsia?
Do you have any of these conditions: toxemia of pregnancy or Preeclampsia or Pre-Eclampsia?
pregnant women
With or without vascular pathology

Exclusion Criteria

refusal to participate
multiple pregnancy
major fetal malformation diagnosed during pregnancy follow-up
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