Standard of Care Therapy With Involved Field Radiation Therapy for Selective Recurrent Ovarian Cancer

  • End date
    May 9, 2023
  • participants needed
  • sponsor
    Yonsei University
Updated on 12 February 2022
neutrophil count
ovarian carcinoma


This study aims to investigate the effect of involved-field radiotherapy for recurrent ovarian cancer after primary standard treatment. We will investigate whether the addition of involved-field RT improves 2-year PFS in those patients than that of historical data (only with other standard salvage treatments as systemic chemotherapy maximum tumor resection).

Condition Recurrent Ovarian Cancer
Treatment Involved-field radiotherapy
Clinical Study IdentifierNCT03618706
SponsorYonsei University
Last Modified on12 February 2022


Yes No Not Sure

Inclusion Criteria

Pathologically confirmed ovarian carcinoma
Patients who received "standard treatment" for each stage as a primary treatment
No. of recurrent lesions
If, all in lung, or intra-abdominal or pelvis organs - 5 If, any in liver
bone, or spinal cord - 2
Size of recurrent lesions 5 cm
All recurrent lesions are available for involved-field radiotherapy
Within 60 days before enrollment
Absolute neutrophil count ANC 500 / mm3
Platelet 50,000 / mm3
Hb 8.0 g / dl
Good performance status (ECOG 0-1)

Exclusion Criteria

Brain metastasis
Diffuse peritoneal carcinomatosis
Malignant pleural effusion
History of previous salvage radiotherapy for recurrent lesions
History of other malignancy or severe/unstable medical condition
Clear my responses

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