Last updated on March 2019

Psoriasis Longitudinal Assessment and Registry (PSOLAR)


Brief description of study

The purpose of this study is to further evaluate the safety of infliximab, ustekinumab, and guselkumab in patients with plaque psoriasis, and other all forms of psoriasis (such as plaque psoriasis and psoriatic arthritis occurring together). The registry study will track the behavior of the disease in response to other therapies, such as other biologic drugs. The registry will also evaluate clinical outcomes; disease characteristics, including physician reported assessment of psoriatic arthritis (PsA); quality of life, and potential risks for patients who may receive standard therapies for psoriasis.

Detailed Study Description

PSOLAR is an 8 year registry study. A registry is an observational study that evaluates the status of a disease. This registry study will only include patients who volunteer to take part. About 4000 infliximab-exposed patients, 4000 ustekinumab-exposed patients and as well as a comparable number of patients (4000) on other standard of care psoriasis therapies (e.g. Etanercept) and/or psoriasis treatments (e.g. topical or light therapy treatments) will take part in the registry study, internationally. Additionally, enrollment will be opened to include at least 2,000 guselkumab-exposed patients and up to 2,000 patients exposed to IL-17 inhibitors (example, secukinumab, ixekizumab, brodalumab). The Registry does not require any study-specific testing, but may capture test information (e.g. laboratory tests, X-rays) that are collected as part of normal routine care for the registry program. Patient information will be collected at the enrollment visit and about every 6 months thereafter. At enrollment, information on demographics (e.g. gender, race, date of birth), medical history and family medical history, details of past and current psoriasis treatments (e.g. infliximab and standard therapy), and current medication regimens will be collected. Clinical follow-up will be based on observations from physical examination, clinical disease status, Quality of Life assessment (e.g. Dermatology Life Quality Index, Hospital Anxiety and Depression Scale, EQ-5D (EuroQoL-5D is a Quality of Life Questionnaire) Health Questionnaire Scale, Employment/Productivity Health Economic Questionnaire), current medications, and any adverse events/problems reported. During each six -month follow-up visit with the study doctor, information collected will include observations from physical examination, updates on clinical disease status, Quality of life assessments, medications and adverse events/problems. No study agents will be administered in this registry. All patients will receive standard of care treatments prescribed by the patient's physician.

Clinical Study Identifier: NCT00508547

Contact Investigators or Research Sites near you

Start Over

Tennessee River Dermatology

Florence, AL United States
  Connect »

Northeast Dermatology

Huntsville, AL United States
  Connect »

Ruth A. Yates M.D.

Huntsville, AL United States
  Connect »

Horizon Research

Mobile, AL United States
  Connect »

Affiliated Dermatology

Scottsdale, AZ United States
  Connect »

Sheftel Dermatology

Tucson, AZ United States
  Connect »

Bakersfield Dermatology

Bakersfield, CA United States
  Connect »

Paul Wallace MD

Beverly Hills, CA United States
  Connect »

Sierra Medical Research

Clovis, CA United States
  Connect »

Edwin M. Hamlin M.D.

Fresno, CA United States
  Connect »

Loma Linda Univ Faculty Medic

Loma Linda, CA United States
  Connect »

Clinica Medica San Miguel

Los Angeles, CA United States
  Connect »

Dermatology Research Associates

Los Angeles, CA United States
  Connect »

Menkes Cosmetic Dermatology

Mountain View, CA United States
  Connect »

Redding Dermatology

Redding, CA United States
  Connect »

Palos Verdes Dermatology

Rolling Hills Estates, CA United States
  Connect »

MedDerm Associates

San Diego, CA United States
  Connect »

Therapeutics Clinical Research

San Diego, CA United States
  Connect »

MD Solutions Medical Corp

Sherman Oaks, CA United States
  Connect »

Cosmetic & Laser center

Valley, CA United States
  Connect »

Colorado Springs Dermatology Clinic, PC

Colorado Springs, CO United States
  Connect »

Kenneth J. Maiocco, M.D.

Bridgeport, CT United States
  Connect »

University of Connecticut

Farmington, CT United States
  Connect »

Burke Dermatology

Newark, DE United States
  Connect »

Delaware Valley Dermatology

Wilmington, DE United States
  Connect »

George Washington University

Washington, WA United States
  Connect »

Horwitz Dermatology

Aventura, FL United States
  Connect »

Tory P. Sullivan, M.D., PA

Aventura, FL United States
  Connect »

VA Healthcare System Bay Pines

Bay Pines, FL United States
  Connect »

Weiss Skin Institute

Boca Raton, FL United States
  Connect »

Dermatology of Boca, LLC

Boca Raton, FL United States
  Connect »

Study Protocol Inc.

Boynton Beach, FL United States
  Connect »

Dermatology Associates In Research

Coral Gables, FL United States
  Connect »

Brent M. Schillinger, MD, PA

Delray Beach, FL United States
  Connect »

Virginia Street Dermatology

Dunedin, FL United States
  Connect »

Michael J. Bernhardt, M.D., P.A.

Jacksonville, FL United States
  Connect »

Ameriderm Research

Jacksonville, FL United States
  Connect »

MIMA

Melbourne, FL United States
  Connect »

Wayne R Porter, MD PA

North Miami Beach, FL United States
  Connect »

Park Avenue Dermatology

Orange Park, FL United States
  Connect »

Gulfcoast Dermatology

Panama City, FL United States
  Connect »

Snyder and Le, MD, PA

Pembroke Pines, FL United States
  Connect »

Forman Dermatology

Tampa, FL United States
  Connect »

Dermatology Vein Institute

Alpharetta, GA United States
  Connect »

Dermatology Consultants PC

Atlanta, GA United States
  Connect »

Inverness Dermatology

Birmingham, GA United States
  Connect »

David E Schoenfeld M.D., PC

Carrollton, GA United States
  Connect »

East Metro Dermatology

Conyers, GA United States
  Connect »

Family Dermatology, PC

Lilburn, GA United States
  Connect »

John David Kayal, MD

Marietta, GA United States
  Connect »

Alan Olmstead, MD, CHTD

Twin Falls, ID United States
  Connect »

Altman Dermatology Associates

Arlington Heights, IL United States
  Connect »

Christie Clinic

Champaign, IL United States
  Connect »

Northwestern

Chicago, IL United States
  Connect »

SKINQRI

Lincolnshire, IL United States
  Connect »

Schaumburg Dermatology

Schaumburg, IL United States
  Connect »

SIU School of Medicine

Springfield, IL United States
  Connect »

Dundee Dermatology

West Dundee, IL United States
  Connect »

Central Dupage Hospital

Winfield, IL United States
  Connect »

Deaconess Clinic Mt. Pleasant

Evansville, IN United States
  Connect »

Indiana University Medical Center

Indianapolis, IN United States
  Connect »

A. David Gerstein, M.D.

Indianapolis, IN United States
  Connect »

The Dermatology Center PSC

New Albany, IN United States
  Connect »

Kansas Medical Clinic

Topeka, KS United States
  Connect »

Dr Melissa Knuckles

Corbin, KY United States
  Connect »

Mapi Group

Lexington, KY United States
  Connect »

David Strobel, M.D.

Catonsville, MD United States
  Connect »

Greater Washington Dermatology

Rockville, MD United States
  Connect »

Lawrence R. Feldman, M.D.

Westminster, MD United States
  Connect »

Kenneth M Reed MD PC

Quincy, MA United States
  Connect »

David Fivenson MD, Dermatology

Ann Arbor, MI United States
  Connect »

Drs Iacobelli & DiGregorio PC

Clinton Township, MI United States
  Connect »

Barry I Auster, MD, PC

Farmington, MI United States
  Connect »

Dr. Walter Barkey

Flint, MI United States
  Connect »

Hamzavi Dermatology

Fort Gratiot, MI United States
  Connect »

Silverton Skin Institute

Grand Blanc, MI United States
  Connect »

Dermatology Center of Grand Rapids

Grand Rapids, MI United States
  Connect »

Skincare Associates PC

Monroe, MI United States
  Connect »

Somerset Skin Centre

Troy, MI United States
  Connect »

Grekin Skin Institute

Warren, MI United States
  Connect »

West County Dermatology Inc.

Chesterfield, MO United States
  Connect »

St. Louis University

Saint Louis, MO United States
  Connect »

Central Dermatology

Saint Louis, MO United States
  Connect »

Associated Dermatology

Helena, MT United States
  Connect »

Woodson Dermatology

Henderson, NV United States
  Connect »

H.L. Greenberg, M.D., LTD

Las Vegas, NV United States
  Connect »

Nashua Dermatology

Nashua, NH United States
  Connect »

Windsor Dermatology, PC

East Windsor, NJ United States
  Connect »

Aesthetic Dermatology

Marlton, NJ United States
  Connect »

The Dermatology Group, PC

Verona, NJ United States
  Connect »

Jeffrey LaDuca, MD, PC

Auburn, NY United States
  Connect »

Gary M. Hahn, M.D

Commack, NY United States
  Connect »

Garden City Dermatology, P.C.

Garden City, NY United States
  Connect »

Robert L. Bruckstein MDPC

Lawrence, NY United States
  Connect »

Mercer Street Medical

New York, NY United States
  Connect »

NYU School of Medicine

New York, NY United States
  Connect »

Noah Scheinfeld, M.D., PLLC

New York, NY United States
  Connect »

Greene Richard M MD

Rochester, NY United States
  Connect »

Genesee Valley Group Health

Rochester, NY United States
  Connect »

Thomas O McMeekin, MD P.C

Rochester, NY United States
  Connect »

Dermatique Dermatology

Smithtown, NY United States
  Connect »

Dermatology Associates, Of New York

Staten Island, NY United States
  Connect »

Joseph D. Sutton, M.D., PC

Suffern, NY United States
  Connect »

Farah Dermatology Center

Syracuse, NY United States
  Connect »

Alan Schliftman MD, PC Dermatology

White Plains, NY United States
  Connect »

Buffalo Medical Group

Williamsville, NY United States
  Connect »

George Fisher

Hickory, NC United States
  Connect »

PMG Research of Raleigh

Raleigh, NC United States
  Connect »

Jeffrey M Suchniak

Rocky Mount, NC United States
  Connect »

Atlantic Dermatology Associates

Wilmington, NC United States
  Connect »

Salem Medical Research Group

Winston-Salem, NC United States
  Connect »

Curtis W. Hawkins, MD

Akron, OH United States
  Connect »

Mid-Ohio Dermatology, Inc.

Columbus, OH United States
  Connect »

Martha Ann Hickmann, M.D.

Dayton, OH United States
  Connect »

Timothy J. Storer, M.D.

Delaware, OH United States
  Connect »

Frederick C. Smith Clinic

Marion, OH United States
  Connect »

Brodell Medical Inc.

Warren, OH United States
  Connect »

University of Oklahoma-Tulsa

Oklahoma City, OK United States
  Connect »

Park Avenue Dermatology

Coos Bay, OR United States
  Connect »

Andrew K. Pollack & Associates

Fort Washington, PA United States
  Connect »

Paddington Testing Co, Inc.

Philadelphia, PA United States
  Connect »

Associates in Dermatology

Pittsburgh, PA United States
  Connect »

Vu Skin Research

Pittsburgh, PA United States
  Connect »

Fort Mill Dermatology LLC

Fort Mill, SC United States
  Connect »

Westside Dermatology

Spartanburg, SC United States
  Connect »

James Turner, MD, PHD, PC

Bartlett, TN United States
  Connect »

Lawrence H. Reid, MD, PC

Greeneville, TN United States
  Connect »

Aftergut Dermatology

Cedar Hill, TX United States
  Connect »

Heights Dermatology

Houston, TX United States
  Connect »

West Houston Dermatology PA

Houston, TX United States
  Connect »

Longview Dermatology

Longview, TX United States
  Connect »

University of Utah

Salt Lake City, UT United States
  Connect »

Glenn H. Fuchs, M.D., PC

Arlington, VA United States
  Connect »

Virginia Clinical Research

Norfolk, VA United States
  Connect »

Ken Tompkins Dermatology

Virginia Beach, VA United States
  Connect »

Island County Dermatology

Coupeville, WA United States
  Connect »

Skagit Valley Medical Center

Mount Vernon, WA United States
  Connect »

Dr. James Hu

Seattle, WA United States
  Connect »

Allenmore Medical Center

Tacoma, WA United States
  Connect »

Cascade Eye & Skin Center

University Place, WA United States
  Connect »

Eastern Washington Dermatology

Walla Walla, WA United States
  Connect »

Great Lakes Dermatology, SC

Pleasant Prairie, WI United States
  Connect »

Lumipiel

Caba, Argentina
  Connect »

Dermasur

Lomas De Zamora, Argentina
  Connect »

LKH Feldkirch

Feldkirch N/A, Austria
  Connect »

Praxis Gassner

Klagenfurt, Austria
  Connect »

Stratica Medical

Edmonton, AB Canada
  Connect »

Enverus Medical

Surrey, BC Canada
  Connect »

Winnipeg Clinic

Winnipeg, MB Canada
  Connect »

Ruth MacSween M.D.

Kingston, ON Canada
  Connect »

Specilaized Dermatology

St Catherines, ON Canada
  Connect »

Manna Research

Toronto, ON Canada
  Connect »

Isabelle Delorme Inc.

Drummondville, QC Canada
  Connect »

Centro Medico Skin-Med

Santiago - Las Condes, Chile
  Connect »

Nemocnice Jihlava

Jihlava N/A, Czechia
  Connect »

Haemek

Afula, Israel
  Connect »

Consultorio Privado

Estado De Mexico, Mexico
  Connect »

Centrum Oosterwal

Alkmaar, Netherlands
  Connect »

AMC

Amsterdam Zuidoost, Netherlands
  Connect »

Deventer Ziekenhuis

Deventer, Netherlands
  Connect »

Zorggroep Twente

Hengelo, Netherlands
  Connect »

AKD d.o.o.

Ljubljana, Slovenia
  Connect »

Dermadent d.o.o.

Ljubljana, Slovenia
  Connect »

Medical Center Rogaska

Rogaska Slatina, Slovenia
  Connect »

Fundaci n Medica de Cipoletti

Cipoletti, Neuquén, Argentina
  Connect »

CEDIC Centro de Investigaciones Clinicas

Ciudad Autónoma De Buenos Aires, Argentina
  Connect »

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.