Study of Pembrolizumab Following TACE in Primary Liver Carcinoma (PETAL)

  • participants needed
  • sponsor
    Imperial College London
Updated on 5 July 2022


Open label, single arm, multi-centre study of pembrolizumab following trans-arterial chemoembolization (TACE). Twenty-six to 32 evaluable participants with primary liver cancer (hepatocellular cancer; HCC) will be assessed. The primary objective is to determine the safety and tolerability of pembrolizumab following TACE. The secondary objective is to evaluate the efficacy of pembrolizumab following TACE by improving progression-free survival rates as measured by modified response evaluation criteria in solid tumours (mRECIST) criteria.

Condition Primary Liver Carcinoma
Treatment Pembrolizumab, Trans-arterial chemoembolization
Clinical Study IdentifierNCT03397654
SponsorImperial College London
Last Modified on5 July 2022

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