Post-operative Urinary Retention (POUR) Following Thoracic Surgery (POUR)

  • End date
    May 2, 2024
  • participants needed
  • sponsor
    Hackensack Meridian Health
Updated on 19 October 2022
Accepts healthy volunteers


Inability to urinate a common complication that happens to many patients after a surgery, especially in men over 60 years of age who undergo surgery on their chest. Urinary retention is uncomfortable, increases anxiety, increases hospital length of stay, and leads to more procedures such as putting in a bladder catheter (Foley). This is uncomfortable, and can lead to bleeding, infection, damage to the urethra and/or bladder and bladder spasm. The goal of this study is to attempt to prevent inability to urinate by giving patients a medication called Flomax (Tamusolin) every day beginning a week before surgery. That medication relaxes the prostate. It's approved by the Food and Drug Administration (FDA) to improve urinary flow in those with enlarged prostates. It is also commonly used in patients with bladder problems due to inability to urinate who have required a Foley.


Post-operative urinary retention (POUR) in older men who undergo a thoracic surgical procedure occurs in a significant proportion of patients (25% at Hackensack University Medical Center in men >60) and is a significant management problem. Typically, this complication needs to be treated with placement of a bladder catheter (foley). In addition to the discomfort of placing a foley in an awake patient, these patients are at a significantly increased risk of a catheter associated urinary tract infection (CAUTI), potential genito-urinary injury during the placement, and bladder muscle damage due to distention.

The goal of this study is to investigate whether the use of Tamusolin could lower the high incidence of POUR in older men undergoing a thoracic surgical procedure.

The investigators hypothesize that pre-operative administration of Tamusolin (Flomax, 0.4mg/day x 1 week), with ongoing use post-operatively until normal voiding resumes, will result in a significant decrease in the incidence of POUR after a thoracic surgical procedure.

Condition Urinary Retention
Treatment Tamsulosin
Clinical Study IdentifierNCT03609580
SponsorHackensack Meridian Health
Last Modified on19 October 2022


Yes No Not Sure

Inclusion Criteria

Inclusion criteria
≥60 years old Planned surgical procedure of a minimally invasive thoracic surgical
procedure (wedge resection, segmentectomy, lobectomy, pleural biopsy, or pleurodesis)
Surgery scheduled more than 3 days from the time of consent
Patient eligibility criteria should be listed. (Medical criteria, age, demonstration of
disease, ailment, etc., proof of failure using standard therapy, laboratory assessments for
eligibility, etc.)

Exclusion Criteria

Using Flomax already
Allergy to Flomax or sulfa drugs
Current use of alpha blockers or alpha agonists
Resting systolic blood pressure <100
Known diagnosis of congestive heart failure and valvular heart disease
History of prostate surgery (prostatectomy, trans-urethral resection)
Orthostatic hypotension of >20mm Hg (millimeters of mercury) Systolic and/or 10mm Hg
diastolic pressure from sitting to standing (after 2 minutes of standing) as measured
at the time of consent
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact


Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note