The Use of Technology to Improve MS Clinical Trials and Patient Care

  • STATUS
    Recruiting
  • End date
    Dec 31, 2024
  • participants needed
    150
  • sponsor
    Johns Hopkins University
Updated on 27 May 2022
interferon
MRI
weakness
fingolimod
disease or disorder
glatiramer acetate
dimethyl fumarate
teriflunomide

Summary

Many patients with multiple sclerosis (MS) experience "relapses" of disease activity during which they have increased numbness, weakness, visual problems, or other symptoms. If a person with MS has new symptoms that are concerning to them, their doctor may want to see them in the office in order to confirm that these symptoms are due to a true "relapse" of activity before starting relapse treatment. This requirement can be frustrating for patients, who may have to take time off from work or travel long distances for such unexpected doctors' visits. In this study, the investigators will use input from patients with MS and MS physicians to create a relapse questionnaire that can be used to confirm a relapse has occurred. The investigators will also evaluate if having a more direct line of communication with the provider's office improves overall patient care and satisfaction.

Description

This research is being done to study if a relapse questionnaire for people with multiple sclerosis (MS) may help more easily determine if a relapse has occurred.

A further goal of this study is to determine if receiving periodic messages from the doctor's office, as well as having the direct contact information of a person in the office, improves the care of the patients and their experience thereof.

Details
Condition Multiple Sclerosis
Treatment Communication with the clinic
Clinical Study IdentifierNCT02454907
SponsorJohns Hopkins University
Last Modified on27 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

English speakers
Relapsing-remitting MS (2010 criteria)
Expanded Disability Status Scale (EDSS) ≤6.0
Possession of a smartphone OR of a mobile telephone with text messaging AND an e-mail account AND web access OR willingness to be provided with, and utilize, a smartphone for the duration of the study
In the two years before screening
at least two relapses, OR one relapse and two new lesions (unrelated to relapse symptoms)
on magnetic resonance imaging (MRI), OR RRMS (MAGNIMS 2010 criteria) onset within the past
year with no exposure to disease modifying therapies (DMT)
Patient is starting one of the following MS therapies: injectable (subcutaneous
interferon beta or glatiramer acetate) or oral (fingolimod, teriflunomide, or dimethyl
fumarate) therapies
Lives within 100 miles of Johns Hopkins Medical Center (Baltimore, MD)
Relapse and MRI activity occurred while untreated or despite one single treatment, and
no change in therapy since that activity

Exclusion Criteria

History of DMT exposure if MAGNIMS 2010 criteria used to enroll patients with disease
onset in the past year, or change in MS therapy since qualifying relapse/MRI criteria
occurred
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note