Last updated on September 2018

Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Fibromyalgia | Myofascial Pain Syndrome | Myofascial Pain | Somatization Disorder | TEMPOROMANDIBULAR JOINT DISORDER | Headache
  • Age: Between 18 - 65 Years
  • Gender: Male or Female

Inclusion Criteria:

  • 18-65 years of age
  • Ability to give informed consent
  • Myofascial pain of masticatory muscles as defined according to the RDC/TMD criteria
  • Baseline pain measured by the subject 3.5/10 on visual analog scale

Exclusion Criteria:

  • Baseline pain measured by the subject <3.5/10 on visual analog scale
  • Central/Neuropathic pain disorder affecting the masticatory muscles
  • Temporomandibular Joint Arthralgia that is more severe than the myofascial pain disorder affecting the masticatory muscles
  • Previous Temporomandibular Joint Surgery
  • Systemic arthropathies
  • Fibromyalgia
  • Allergy to study medications
  • Traumatic injury of masticatory muscles or temporomandibular joint within last 12 months
  • Mandibular fracture within last 12 months
  • Pregnancy or breast feeding
  • Cervical radiculopathy or surgery
  • Prior botox injection in the masticatory muscles
  • Initiation of additional treatment of MPD within the past 3 months

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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