Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer

  • STATUS
    Not Recruiting
  • End date
    Mar 1, 2023
  • participants needed
    60
  • sponsor
    Pfizer
Updated on 31 March 2021
Investigator
Pfizer CT.gov Call Center
Primary Contact
Highlands Oncology Group (1.2 mi away) Contact
+140 other location

Summary

A PHASE 2, NON RANDOMIZED, OPEN LABEL, SINGLE ARM, MULTI CENTER STUDY OF TALAZOPARIB FOR NEOADJUVANT TREATMENT OF GERMLINE BRCA1/2 MUTATION PATIENTS WITH EARLY HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 NEGATIVE BREAST CANCER

Description

TALAZOPARIB (PARP INHIBITOR) FOR NEOADJUVANT TREATMENT OF GERMLINE BRCA1/2 MUTATION PATIENTS WITH EARLY HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 NEGATIVE BREAST CANCER. THIS IS A MONOTHERAPY TREATMENT FOR 24 WKS FOLLOWED BY SURGERY TO EVALUATE PATHOLOGICAL COMPLETE RESPONSE.

Details
Condition Early Breast Cancer
Treatment Talazoparib
Clinical Study IdentifierNCT03499353
SponsorPfizer
Last Modified on31 March 2021

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