Last updated on June 2020

Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer


Brief description of study

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming back.

Detailed Study Description

Women with node positive breast cancer normally will receive endocrine therapy and some may receive chemotherapy to help prevent the cancer from coming back. Many women will also receive radiotherapy to the whole breast/chest area and the surrounding lymph glands (called regional radiotherapy). No one really knows whether patients with low risk breast cancer need to receive regional radiotherapy. Some women may be getting regional radiotherapy who do not need it. These women may be exposed to the side effects of their treatment without benefit.

Clinical Study Identifier: NCT03488693

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Lovelace Radiation Oncology

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Saint Francis Cancer Center

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West Columbia, SC United States
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South Jordan, UT United States
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Augusta Health Cancer Center

Fishersville, VA United States
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Sheboygan, WI United States
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Wisconsin Rapids, WI United States
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South Pasadena, CA United States
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Tampa, FL United States
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West Michigan Cancer Center

Kalamazoo, MI United States
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Minneapolis, MN United States
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Community Medical Center

Toms River, NJ United States
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New York, NY United States
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Farmington, UT United States
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Grafton, WI United States
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Green Bay, WI United States
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Milwaukee, WI United States
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Jacksonville, FL United States
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Weston, FL United States
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Littleton, CO United States
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Crossroads Cancer Center

Effingham, IL United States
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Mary Imogene Bassett Hospital

Cooperstown, NY United States
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Chardon, OH United States
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Westlake, OH United States
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Houston, TX United States
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Johnson Creek, WI United States
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Carmel, IN United States
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Altru Cancer Center

Grand Forks, ND United States
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Recruitment Status: Open


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