The purpose of the study is to determine if lipoic acid can preserve mobility and protect the brain in progressive forms of multiple sclerosis.
This two-year study will determine if daily oral intake of lipoic acid will prove superior to placebo in reducing injury to the brain and maintaining mobility in progressive MS. Mobility will be assessed with the timed 25-foot walk test and 2-minute timed walk test as well as fall counts. Neuroprotection will be measured by the extent of brain volume loss seen on MRI.
Condition | Multiple Sclerosis |
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Treatment | Placebo, Lipoic acid |
Clinical Study Identifier | NCT03161028 |
Sponsor | VA Office of Research and Development |
Last Modified on | 5 March 2022 |
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