Inflammatory Biomarkers of Pediatric Pulmonary Hypertension

  • STATUS
    Recruiting
  • days left to enroll
    66
  • participants needed
    60
  • sponsor
    The Hospital for Sick Children
Updated on 3 June 2022
heart disease
Accepts healthy volunteers

Summary

To investigate if the inflammatory protein, high mobility group box 1 (HMGB1), along with other inflammatory mediators, is elevated in pediatric patients with congenital heart disease (CHD) and pulmonary hypertension as compared to those with CHD alone, or with healthy controls.

Details
Condition Hypertension, Pulmonary
Treatment Blood test
Clinical Study IdentifierNCT03581695
SponsorThe Hospital for Sick Children
Last Modified on3 June 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

patients of any age with congenital cardiac disease coming for catheterization of the
right heart, or both the right and left heart

Exclusion Criteria

active systemic infection
current active cancer
active cancer treatment
prior bone marrow transplant
prior solid organ transplant
Clear my responses

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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