Last updated on July 2020

Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Systemic Inflammation | Cardiopulmonary Bypass
  • Age: Between 21 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Undergoing cardiac surgery with planned cardiopulmonary bypass
  • Additive Euroscore II 3 OR at least 3 surgical cardiac interventions are planned
  • Ability to provide informed consent (not incapacitated)

Exclusion Criteria:

  • Already on renal replacement therapy
  • Patients with chronic kidney disease defined as estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2 [ CKD stage > 3 ]
  • Patients who are pregnant
  • Concurrent enrollment in another clinical trial
  • Known allergic reaction to bovine alkaline phosphatase or patient is vegetarian or vegan
  • Patients with ongoing infections or current use of steroids

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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