Last updated on July 2020

Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase

Brief description of study

Study should demonstrate that alkaline phosphatase reduces the incidence and extent of acute kidney injury after cardiopulmonary bypass (CPB) as defined by the AKIN criteria.

Detailed Study Description

After cardiac surgery under cardiopulmonary bypass (CPB) patients often show impairments of the immune system. Compared to placebo, CPB patients given alkaline phosphatase will have reduced composite endpoint of acute kidney injury, late extubation, gastrointestinal or neurological complications or death within 30 days.

Clinical Study Identifier: NCT03050476

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Recruitment Status: Open

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