Testicular Growth During Puberty in Boys With and Without a Left-sided Varicocele

  • End date
    Sep 23, 2022
  • participants needed
  • sponsor
    Universiteit Antwerpen
Updated on 23 January 2021


Prospective observational study.

A varicocele is defined as a dilatation of the veins in the plexus pampiniformis in the testicles. Varicoceles are a diagnostic dilemma and a therapeutic challenge. Most of the boys with a varicocele don't show any symptoms, but approximately 15-20% experience some sort of infertility later during their life. There still isn't any consensus on when treating the patient is the right choice. Reliable scientific research about parameters able to predict the later stages of the boy with a varicocele is therefore needed. The purpose of this study is to how testicular growth could predict the outcome of boys with a varicocele.

During this study, testicular growth in boys with and without a left-sided varicocele will be examined in different schools using ultrasound to measure the testicular volumes, the PRF and the TAI to be able to collect sufficient data with the purpose to be able to predict whether testicular growth is a significant predictor on the progression of a varicocele.

Condition Varicocele, Vascular Diseases, Scrotal Disorder
Treatment ultrasound
Clinical Study IdentifierNCT03540056
SponsorUniversiteit Antwerpen
Last Modified on23 January 2021


Yes No Not Sure

Inclusion Criteria

Is your age between 11 yrs and 20 yrs?
Are you male?
Do you have any of these conditions: Varicocele or Scrotal Disorder?
Do you have any of these conditions: Vascular Diseases or Scrotal Disorder or Varicocele?
Boys aged 11-16 years without any evidence of a current or past pathology influencing testicular growth

Exclusion Criteria

Boys with a current or past inguinoscrotal pathology (varicocele, testicular microlithiasis, cryptorchidism, retractile testis, orchidectomy, testicular torsion, orchitis or epididymitis, hypospadias, inguinal hernia, oeprated varicocele, hydrocele and epididymal cysts)
Boys with evidence of disorders influencing testicular growth (e.g. growth disorders)
Boys with missing or incomplete data on Tanner stages for genital development
Boys with a psychiatric disorder
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