Cortisone Shots for Neck Pain

  • End date
    Dec 1, 2023
  • participants needed
  • sponsor
    Stanford University
Updated on 27 May 2022


The purpose of this study is to determine if cortisone shots in the neck are helpful in patients with certain MRI findings. Additionally, the investigators hope to learn if cervical facet joint steroid injections are beneficial in the subset of patients with MRI findings consistent with facet joint synovitis.

Condition Neck Pain, Cervicalgia, Facet Joint Pain
Treatment Intra-articular cervical zygapophyseal joint injection
Clinical Study IdentifierNCT03534531
SponsorStanford University
Last Modified on27 May 2022


Yes No Not Sure

Inclusion Criteria

at least 18 years old
Patient who will be getting a neck cortisone shot for pain that has been there for at least 4 weeks
A specific MRI finding (increased Short Tau Inversion Recovery signal) around 1 or more of the joints in the neck

Exclusion Criteria

Those receiving disability, worker's compensation, or are involved in litigation related to their pain
Those unable to read English and complete the assessment instruments
Those unable to attend follow up appointments
The patient is incarcerated
Grade 2 or greater spondylolisthesis at the involved or adjacent segments
History of prior posterior cervical surgery. Anterior cervical surgery is not an exclusion criteria
Progressive motor deficit, and/or clinical signs of myelopathy
Prior neck cortisone shots within the past 6 months
Possible pregnancy or other reason that precludes the use of fluoroscopy
Allergy to contrast media or local anesthetics
Systemic inflammatory arthritis (e.g., rheumatoid arthritis, ankylosing spondylitis, lupus)
Active infection or treatment of infection with antibiotics within the past 7 days
Chronic widespread pain or somatoform disorder (e.g. fibromyalgia)
Addictive behavior, severe clinical depression, or psychotic features
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