The Effects of Bariatric Surgeries on Glucose Metabolism
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- STATUS
- Recruiting
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- End date
- Aug 27, 2026
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- participants needed
- 200
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- sponsor
- The University of Texas Health Science Center at San Antonio
Summary
The purpose of this study is learn the effect of gastric bypass surgery and sleeve gastrectomy on glucose metabolism mediated by neural and hormonal factors initiated after eating.
Description
The purpose of this study is to determine the weight-independent effects of gastric bypass surgery and sleeve gastrectomy surgery on islet cell response after meal ingestion as mediated by hormonal and neural components of the gut. It will also address the differences between the two procedures.
Such information will be critical for the development of novel approaches for treatment of diabetes as well as improvement of glycemic effects of gastric bypass and sleeve gastrectomy in patients with partial diabetes remission or relapse after complete remission.
Details
| Condition | Post Bariatric Surgery, Gastric Bypass, Sleeve Gastrectomy, Hypoglycemia After Gastric Bypass |
|---|---|
| Treatment | atropine, exendin-(9-39) |
| Clinical Study Identifier | NCT02823665 |
| Sponsor | The University of Texas Health Science Center at San Antonio |
| Last Modified on | 27 August 2023 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
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