Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia (OPPAÎ)

  • STATUS
    Recruiting
  • days left to enroll
    84
  • participants needed
    128
  • sponsor
    University Hospital, Toulouse
Updated on 25 March 2022
pneumonia
fever
chest pain
COPD
dyspnea
pao2
chronic obstructive pulmonary disease
oximetry
cough
shortness of breath
hypothermia

Summary

Hypoxemic pneumonia is a major cause of hospitalization in Pulmonology. The patient's dependency on oxygen prevents early discharge from the hospital. An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. This system has proven to be particularly effective with chronic obstructive pulmonary disease (COPD) patients, by decreasing the time spent in hypoxia and hyperoxia, and by accelerating the weaning of oxygen. Our hypothesis is that automated oxygen therapy leads to a diminution on the length of hospital stay.

Description

Prolonged hospitalization has many consequences, including loss of autonomy and nosocomial infection. Moreover, these complications themselves lead to an extension of the length of stay. This has an impact on the cost of care: several studies have shown that hospitalization is the most costly factor in the management of pneumonia, and that even a small amount of hospital stay, led to significant financial savings. Automated oxygen therapy is a device that automatically adjusts with the saturation the amount of oxygen administered. Investigator hypothesis is that automated oxygen therapy could shorten the length of stay of patients hospitalized for hypoxemic pneumonia. One group of patients will receive the automated oxygen therapy and the other group will receive the standard Oxygen therapy. The investigator will compare in each group the average length of stay, the duration of oxygen therapy, the time spent outside of the target saturation, the cost on the medical-economic level and the patient's experience.

Details
Condition Pneumonia, Pneumonia, Ventilator-Associated, Length of Stay
Treatment O2 automated, O2 standard
Clinical Study IdentifierNCT03527992
SponsorUniversity Hospital, Toulouse
Last Modified on25 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Adult
Patient living at home or in an institution
Patient hospitalized for less than 48 hours
Pneumonia defined (according to the 2006 French-speaking infectious pneumology society (SPILF) criteria) by
respiratory functional symptoms (cough, sputum, dyspnea, chest pain) and
Hyperthermia >38,5°C or hypothermia <36°C and
Radiological Signs of Pneumonia
Hypoxia : SpO2 < 94% in ambient air and/or PaO2< 60 mmHg in ambient air

Exclusion Criteria

Pneumonia acquired at the hospital
Patient hospitalized in another department more than 48 hours before admission
Chronic respiratory failure
Active neoplasia
Patients undergoing oxygen therapy and / or long-term NIV
Associated cardiac decompensation (clinical signs and / or NTproBNP> 1800ng / mL) (3
Initial Need for high flow oxygen therapy or ventilatory support (NIV, VI)
Difficulties expected from home support
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