Overnight Fasting After Completion of Therapy: The OnFACT Study

  • End date
    Apr 3, 2024
  • participants needed
  • sponsor
    Memorial Sloan Kettering Cancer Center
Updated on 3 June 2022


The purpose of this study is to test whether regularly not eating for at least 14 hours overnight ("intermittent fasting") is feasible and can improve blood sugar.

Condition Childhood Cancer Survivors
Treatment Usual Care, prolonged overnight fasting
Clinical Study IdentifierNCT03523377
SponsorMemorial Sloan Kettering Cancer Center
Last Modified on3 June 2022


Yes No Not Sure

Inclusion Criteria

Body mass index is ≥ 18.5 kg/m^2
History of treatment for cancer or related illness diagnosed at ≤ 25 years old
Off of all cancer therapy for ≥ 2 years (excluding treatment for non-invasive or superficial cancers)
History of radiation to the chest, abdomen or total body
Current age ≥18 years
Personal phone with SMS text messaging capability
Willingness to wear an mHealth device, such as a FitBit, for two 7-day periods
Able to perform all study requirements

Exclusion Criteria

Use of any antidiabetic, weight loss, or appetite control medication
Use of any other medication that could impact dietary intake, such as prednisone
Currently fasts 12 hours or more by self-report
Unable to fast due to medical reason such as pregnancy
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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