Last updated on May 2018

Use of Estriol at Distal Third of Vagina Improving Coital Pain in Post-menopause Women


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Sexual Dysfunction | Menopause | Dyspareunia
  • Age: Between 40 - 65 Years
  • Gender: Female

Inclusion Criteria:

  • Women with a clinical diagnosis of menopause
  • FSH> 40 milli-International unit (mIU/ml)
  • Having sex including penetration of penis into vagina
  • Pain during penetration
  • Active sexual partners
  • Stable relationship.

Exclusion Criteria:

  • Previous use of steroids in genital area in the last month
  • Thromboembolism history
  • Renal insufficiency
  • Cholestatic jaundice
  • Degenerative vulvar pathology
  • Breast cancer
  • Endometrial cancer
  • Vulvar cancer
  • Vaginal cancer history
  • Prior radiotherapy to the genital region
  • Smoking
  • Acute urogenital infections
  • Vulvovaginitis
  • Urinary tract infection
  • Genital herpes
  • Genital prolapse grades II, III and IV by Baden Walker
  • Systemic hormonal therapy in the last three months
  • Use of antidepressants drugs
  • Diabetes
  • Thyroid disorder
  • Cognitive restrictions

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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