Last updated on May 2019

A Safety and Tolerability Study of UBX0101 in Patients With Osteoarthritis of the Knee


Brief description of study

A study to evaluate safety, tolerability, and pharmacokinetics of a single intra-articular injection of UBX0101 in patients diagnosed with painful osteoarthritis of the knee.

Detailed Study Description

This study is a phase 1, randomized, double-blind, placebo-controlled single ascending dose study that will evaluate safety, tolerability, and pharmacokinetics of UBX0101 in patients diagnosed with painful femoro-tibial osteoarthritis.

Patients will be randomly allocated to receive UBX0101 or placebo in 3:1 randomization by dose level (cohort).

The primary objective is to establish the safety and tolerability of UBX0101 given as a single intra-articular injection into the femoro-tibial joint of patients with osteoarthritis.

Clinical Study Identifier: NCT03513016

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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