Last updated on May 2018

Intercostal Liposomal Bupivacaine for the Management of Blunt Chest Wall Trauma


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Fracture of rib | Blunt Chest Wall Trauma | Sternal Fracture
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Anticipated length of stay of at least 72 hours
  • Blunt chest wall trauma with two or more rib or sternal fractures
  • Demonstrated ability to achieve > 50% predicted inspiratory capacity based on ideal body weight using IS within the first 24 hours of admission

Exclusion Criteria:

  • Known allergy to bupivacaine
  • Respiratory failure requiring intubation within 24 hours prior to enrollment
  • Known or suspected atrioventricular nodal blockade process requiring cardiology evaluation or pacemaker placement
  • Hemodynamic instability (defined as new intravenous vasopressor or inotrope requirement or mean arterial pressure < 55 mmHg)
  • Signs of active myocardial ischemia or non-ST elevation MI
  • > 20 rib fractures
  • Weight < 50 kg or > 150 kg
  • Pregnancy
  • Incarceration

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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