Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) (MICCHADO)

  • End date
    Dec 31, 2026
  • participants needed
  • sponsor
    Institut Curie
Updated on 16 March 2022
myeloid leukemia
acute leukemia
bone marrow procedure
brain tumor
ewing's sarcoma
histological diagnosis
childhood cancer
mycn protein
metastatic neuroblastoma
kidney tumors
metastatic osteosarcoma



Prospective, multicentric, open, non-randomised, non-therapeutic, interventional study


To identify and characterise:

  • meaningful molecular genetic alterations,
  • meaningful immunological features of high risk childhood, adolescents and young adult cancers, at diagnosis, during patient treatment and follow-up (time dimension).

Condition Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, Osteosarcoma, Leukemia, Central Nervous System Tumor
Treatment Sampling on blood, bone marrow and cerebrospinal fluid
Clinical Study IdentifierNCT03496402
SponsorInstitut Curie
Last Modified on16 March 2022


Yes No Not Sure

Inclusion Criteria

) Age: patients > 25 years old at diagnosis 2) Absence of patient or parents or legal
representative written informed consent 3) Patient for whom follow-up by the investigating
centre does not appear feasible
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How to participate?

Step 1 Connect with a study center
What happens next?
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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