LimPrOn: Limburg Pre-eclampsia Investigation (LimPrOn)

  • End date
    Dec 2, 2030
  • participants needed
  • sponsor
    Hasselt University
Updated on 3 March 2022
toxemia of pregnancy
Accepts healthy volunteers



Multiple adaptations at the cardiovascular system occurs during pregnancy. In the pregnancy condition pre-eclampsia (PE), this adaptations are abnormal. Five to eight percent of all pregnant women worldwide will develop PE.

PE is a pregnancy condition which is characterized with a high blood pressure (>140/90 mm Hg) and the occurrence of proteinuria (>3g/dl/24h) after 20 weeks of gestation. When untreated, this condition can have severe complications for both mother and child. It's important to monitor women with a high risk for developing PE for an early detection and treatment of this condition.

For this reason, a multicenter study is set up with the following applications:

  1. NICCOMO and Maternal Venous Doppler Echography: impedance cardiograph and an echography of the heart and veins.
  2. Maltron: bio-electronic impedance analyze
  3. Remote monitoring of the high risk patients to become a more intensive follow-up

Number of inclusions: 2000 pregnant women from the prenatal consultations of eight different


Condition Pregnancy, Pre-eclampsia
Treatment Remote Monitoring
Clinical Study IdentifierNCT03509272
SponsorHasselt University
Last Modified on3 March 2022


Yes No Not Sure

Inclusion Criteria

> 10 weeks of pregnancy, primipara and multipara

Exclusion Criteria

< 10 weeks of pregnancy and congenital malformations of the fetus
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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