Last updated on August 2018

A Study to Evaluate Transplantation of Astrocytes Derived From Human Embryonic Stem Cells in Patients With Amyotrophic Lateral Sclerosis (ALS)


Brief description of study

This is a study of transplantation of Astrocytes derived from human embryonic stem cells, in patients with Amyotrophic Lateral Sclerosis (ALS).

There will be no change in the routine ALS treatment of the patients enrolled into the study. Treatment will be administered in addition to the appropriate standard of care treatment.

The study hypothesis is that transplantation of Astrocyte(AstroRx) cells can compensate for the malfunctioning of patients' own astrocytes by restoring physiological capabilities like the reuptake of excessive glutamate, reducing oxidative stress, reducing other toxic compounds, as well as by secreting different neuroprotective factors

Clinical Study Identifier: NCT03482050

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