Addition of Azithromycin to Cefazolin Will Reduce Post CS Infections More Than Cefazolin Only.

    Not Recruiting
  • participants needed
  • sponsor
    Ain Shams University
Updated on 22 January 2021


The good standard antibiotic prophylaxis pre elective C S is cefazolin and this study will approve addition of azithromycin to cefazolin will reduce post CS infections more than cefazolin only.


Patiants and methods


Patients fulfilling the inclusion criteria will be randomized to two groups. Both two group will receive standard prophylaxis antibiotic CEFAZOLIN (zinol) (at a dose of 1 g) 2 hours preoperative.

Control Group:

This group will include 200women undergoing elective cs. In this group, patients will receive standard antibiotic prophylaxis CEFAZOLIN (at a dose of 1 g) and azithromycin (at a dose of 1g) 2 hours preoperative.

Study Group:

This group will include 200women undergoing elective cs. In this group, patients will receive only standard prophylaxis antibiotic(CEFAZOLIN)

Inclusion criteria:

  • Gestational age of 37 0/7 weeks and greater
  • Elective cesarean section
  • Medicaly free pregnant women

Exclusion criteria:

  • a known allergy to azithromycin
  • obstetric complications
  • azithromycin use within 7 days before randomization
  • chorioamnionitis or other infection requiring postpartum antibiotic therapy
  • Pre-gestational diabetes

Condition Randomized Controll Trial
Treatment Azithromycin
Clinical Study IdentifierNCT03502356
SponsorAin Shams University
Last Modified on22 January 2021

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