Hepatitis C (HCV) Cure and Kidney Health

    Not Recruiting
  • participants needed
  • sponsor
    San Francisco Veterans Affairs Medical Center
Updated on 22 January 2021
HIV Infection


The purpose of this study is to learn how 12 weeks of HCV treatment with elbasvir and grazoprevir (brand name Zepatier) impacts your kidney function.


Prospective data collection of 25 Genotype 1 or 4 HCV-infected women from the San Francisco Women's Interagency HIV Study (WIHS) site and 25 Genotype 1 or 4 HCV-infected men from the San Francisco VA Medical Center who are initiated on Zepatier for 12 weeks (Total n=50). For women and men with HCV genotype 1a infection, only those without baseline NS5A resistance mutations will be included. Blood/urine samples will be collected before initiation of treatment, 4 weeks after treatment initiation, 12 weeks after treatment initiation (end of treatment), 24 weeks after treatment initiation to determine Sustained Virological Response (SVR), and at 48 weeks after treatment initiation.

Condition Hepatitis C, Hepatitis C virus
Treatment Elbasvir / Grazoprevir Oral Tablet [Zepatier]
Clinical Study IdentifierNCT03407703
SponsorSan Francisco Veterans Affairs Medical Center
Last Modified on22 January 2021

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