Effect of Vibration on Muscle Properties, Physical Activity and Balance in Children With Cerebral Palsy

  • STATUS
    Recruiting
  • End date
    May 31, 2023
  • participants needed
    44
  • sponsor
    University of Georgia
Updated on 26 March 2022
cerebral palsy
spastic cerebral palsy

Summary

The aim of the 6-month randomized controlled trial, with 6-month no treatment follow-up, is to examine the effects of low-magnitude vibration on muscle, physical activity, and balance in children with spastic cerebral palsy.

Description

Cerebral palsy (CP) is a movement disorder that affects over 800,000 people in the U.S. Due to the limited mobility associated with the disorder, individuals with CP have an increased risk of chronic diseases, such as cardiovascular disease, diabetes mellitus and osteoporosis, compared to the general population. Therefore, identifying treatment strategies is of utmost importance. The aim of this study is to examine the acute and chronic effects of low-magnitude vibration on muscle, physical activity, and balance in children with CP. Fat concentration and muscle will be assessed using imaging techniques. Physical activity will be assessed using activity monitors. Balance will be assessed using clinical and biomechanical tests. Children with CP will be tested at five time points: baseline, 1 and 6 months after standing on a vibration platform daily 10 minutes per day, 1 and 6 months post treatment (7 months and 12 months from baseline, respectively). The findings from the proposed study will help us determine if vibration shows promise as a treatment for the impaired mobility, lower physical activity and higher risk of chronic disease in individuals with CP.

Details
Condition Cerebral Palsy, Spastic
Treatment Vibration Platform, Placebo Platform
Clinical Study IdentifierNCT03484078
SponsorUniversity of Georgia
Last Modified on26 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Spastic cerebral palsy
Independent ambulator without an assistive device (Gross Motor Function Classification System level I or II)

Exclusion Criteria

Prior fractures in both femurs or tibias
Currently taking bisphosphonates
Unable to stand independently
Orthopedic surgery on a lower extremity within the last 6 months
Children with pure athetoid CP
Baclofen pump in the abdomen
Botox treatment within the last year
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