Last updated on February 2019

Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Diabetic Retinopathy | Circadian Dysrhythmia | Melatonin | Circadian Rhythm Sleep Disorder | Unspecified Type
  • Age: Between 40 - 75 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Diabetic patients
  • Age range 40-75 years
  • Participant should be legally competent

Exclusion Criteria:

  • Other known eye disease.
  • Eye disease manifestation during ocular examination.
  • Competing neurologic and systemic conditions affecting retina.
  • Use of any drugs influencing pupillary light reflex and sleep pattern.
  • Refractive error with need of > 6 diopter lenses.
  • Pregnancy
  • Alcohol consumption during the trial
  • Lack of cooperation
  • Allergy to melatonin and/or preservatives in melatonin and placebo
  • Reduced hepatic function
  • Fluvoxamin intake due to drug interaction
  • Consumption of Alpha-1 and beta-1 adnergic antagoists.
  • Alcohol consumption during treatment

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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