Last updated on January 2019

Effect of Orthoses and Underfoot Vibration on Balance in Neuropathy

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Peripheral Neuropathy | Hereditary Peripheral Neuropathy | Charcot-Marie-Tooth Disease
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Clinical or genetically confirmed diagnosis of CMT or related peripheral neuropathy
  2. Mixed sensory and motor presentation
  3. Over 18 years
  4. Able to stand unsupported for five minutes
  5. Able to walk for 50m with or without a walking stick or orthotic devices

Exclusion Criteria:

  1. Presence of other significant neurological disorders (such as multiple sclerosis, cerebrovascular diseases, epilepsy, movement disorders), or major comorbidities (e.g. vestibular dysfunction, use of medication which may affect balance, cognitive impairment, presence of medical conditions in which exercise training may be detrimental).
  2. Presence of peripheral neuropathy caused by a condition other than CMT.
  3. Limb surgery during the six months prior to screening (or planned before final assessment).
  4. Women of child-bearing age if they are pregnant, planning a pregnancy during their time in the study or in the 12 weeks following giving birth. This is due to the effects of pregnancy on balance.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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