Last updated on June 2019

AMG0103 in Subjects With Chronic Discogenic Lumbar Back Pain

Brief description of study

This clinical trial evaluate the safety, tolerability and exploratory efficacy of targeted single injection of AMG0103 in subject with chronic discogenic lumbar back pain

Detailed Study Description

This is a Phase 1b, multicenter, double-blind, single ascending dose study designed to evaluate the safety of AMG0103 in adult male and female subjects with chronic discogenic lumbar back pain.

This protocol anticipates that 8 subjects with symptomatic single level discogenic pain will be enrolled in each of up to 3 dose-escalation cohorts. Subjects in each cohort will receive AMG0103 or Placebo as a targeted, single, intradiscal injection.

Clinical Study Identifier: NCT03263611

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Spine Institute of San Diego

San Diego, CA United States
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Florida Medical Pain Management

Saint Petersburg, FL United States
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Keck Medicine of USC

Los Angeles, CA United States
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Florida Medical Relief

Tampa, FL United States
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