Last updated on May 2019

TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Postpartum Hemorrhage
  • Age: Between 18 - 64 Years
  • Gender: Female

Inclusion Criteria:

  • : adult women admitted for a cesarean delivery before or during labor, at a term 34 weeks,
  • hemoglobin level at the last blood sample >9g/dl,
  • available blood test for Hb and Ht within one week before caesarean delivery,
  • informed signed consent

Exclusion Criteria:

  • previous thrombotic event or preexisting pro-thrombotic disease,
  • epileptic state or history of seizures,
  • presence of any chronic or active cardiovascular disease outside hypertension,
  • any chronic or active renal disease and chronic or active liver disease at risk thrombotic or hemorrhagic, autoimmune disease,
  • sickle cell disease,
  • placenta praevia,
  • placenta accreta/increta/percreta,
  • abruption placentae,
  • eclampsia,
  • HELLP syndrome,
  • significant hemorrhage before cesarean section
  • in utero fetal death,
  • administration of low-molecular-weight heparin or antiplatelet agents during the week before delivery,
  • planned general anesthesia,
  • hypersensitivity to tranexamic acid or concentrated hydrochloric acid,
  • instrumental extraction failure,
  • multiple pregnancy with vaginal delivery of the first child,
  • poor understanding of the French language.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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