Duloxetine for Acute Post-mastectomy Pain

    Not Recruiting
  • participants needed
  • sponsor
    Assiut University
Updated on 24 January 2021


The objective of this study is to evaluate the analgesic effect of oral dulexitine tablet (administered 2 h before surgery) as well as the ideal dose for acute postmastectomy pain.


patients undergoing mastectomy with axillary evacuation will be divided to four groups, Placebo group: received placebo capsule Duloxetine 30: received duloxetine 30 mg capsule Duloxetine 60: received duloxetine 60 mg capsule Duloxetine 90: received duloxetine 90 mg capsule the study medication is administered orall 2 h before surgery. Primary outcome variable: the first postoperative 24 h morphine consumption Secondary outcome: the VAS pain score measured every 4 h in the first 24 h postoperatively.

Condition Acute Pain
Treatment Duloxetine
Clinical Study IdentifierNCT03468348
SponsorAssiut University
Last Modified on24 January 2021

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