Last updated on February 2019

Healthy Overweight & Obese NO 0009-0250

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: *Healthy Patient Studies | Healthy Volunteers
  • Age: Between 22 - 55 Years
  • Gender: Male or Female

If you are able to answer “YES” to the following statements, you may qualify for this study.

  • I am a healthy adult who is overweight or has obesity and no significant medical conditions.
  • I am Male and between 22 and 55 years old.
  • I am Female and between 22 and 45 years old.
  • My BMI is between 27.0 and 39.9 kg/m2 (inclusive).
  • I do not smoke or use any tobacco or nicotine products.  I agree not to smoke for the duration of the study and to abide by the rules of the clinic, which is a non-smoking facility.
  • I have not participated in (nor am I currently participating in) any clinical research study of an approved or non-approved investigational medicinal product within 30 days before screening.
  • I am a Female with regular menstrual cycles (defined as 24-35 day cycles between 1st day of menses for the two most recent menstrual periods).
  • If Female, I am not pregnant or breastfeeding and I do not intend to become pregnant.
  • If Female, I am not post-menopausal.
  • If Female, I am either surgically sterile by tubal ligation, or I agree to use a non-hormonal intrauterine device or diaphragm/cervical cap with spermicide in combination with condom for male partner(s).
  • If Female, I have not used hormonal contraceptives (oral contraceptives, implant or hormonal intrauterine device) within 3 months before screening.
  • If Male, I have had a vasectomy, or, I agree to use a condom with spermicidal foam/gel/cream combined with an approved contraceptive method if my partner is capable of becoming pregnant (e.g., implants, injectables, oral contraceptives, intrauterine devices, diaphragm, or cervical cap with spermicide).
  • If Male, I agree not to donate sperm from screening to 90 days after last dose of study drug.
  • I am able to communicate effectively in English with the study personnel.
  • I do not anticipate a change in lifestyle (e.g., eating, exercise or sleeping pattern) during the study.
  • I do not have a risk of atherosclerotic cardiovascular disease (NOTE: for subjects age 40+).
  • I do not have a history or presence of any cardiovascular disease including stable and unstable angina, myocardial infarction, transient ischaemic attack, stroke, cardiac decompensation, arrhythmias and conduction disorders.
  • I do not have a history or presence of bone disease or an increased risk of bone fracture.
  • I do not have a history or presence of cancer within the last 5 years prior to screening. (NOTE: Except for cured basal and squamous cell skin cancer and in-situ carcinomas.).
  • I do not have a history or presence of sleep apnea.
  • I do not have any special diet requirements and I am willing to eat the food provided while on-site and overnight stays.
  • I have not had any prior obesity surgery and I do not have a gastrointestinal implant.
  • I have not had a clinically significant weight change (e.g., ≥5% change), I have not dieted within 90 days prior to screening, and I am not participating in an organized weight reduction program.
  • I do not have any history of psychiatric disorders (e.g., schizophrenia, bipolar disorder, eating disorders, depression or anxiety).
  • I have not taken any prescription or nonprescription medications, herbal products, or non-routine vitamins within 2 weeks prior to screening. (NOTE: Mild painkillers are allowed until 24 hours before screening).
  • I do not have a history of alcohol abuse, within 12 months of screening (e.g. more than 7 units/weekly for females and more than 14 units/weekly for males).
  • I do not have a history of drug abuse/chemical substance abuse within 12 months before screening.
  • I have not donated blood, donated plasma in the last 60 days or had numerous blood draws within the past 30 days before screening.
  • I do not have a history of any severe or life-threatening allergies or a history of anaphylactic reactions (e.g., food or medications or latex).
  • I have not had problems having blood drawn in either arm, venous access or finger pricks.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.