A Safety, PK and Efficacy Study of CC-92480 Monotherapy and in Combination With Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)

  • STATUS
    Recruiting
  • End date
    Feb 8, 2027
  • participants needed
    201
  • sponsor
    Celgene
Updated on 4 October 2022
cancer
bone marrow transplant
measurable disease
maintenance therapy
bone marrow procedure
dexamethasone
lenalidomide
progressive disease
neutrophil count
proteasome inhibitor
refractory multiple myeloma
pomalidomide
immunotherapeutic agent

Summary

This is an open-label, multi-center, international, Phase 1/2 study to assess the safety, PK and efficacy of CC-92480 monotherapy and in combination with dexamethasone in subjects with relapsed and refractory multiple myeloma (RRMM).

RRMM patient previously treated with at least 3 prior regimens including lenalidomide or pomalidomide, a proteasome inhibitor and a CD38 antibody will be eligible.

Details
Condition Multiple Myeloma
Treatment Dexamethasone, CC-92480
Clinical Study IdentifierNCT03374085
SponsorCelgene
Last Modified on4 October 2022

Eligibility

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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