Peripheral Nerve Blocks for Above-the-knee Amputations

  • STATUS
    Recruiting
  • days left to enroll
    3
  • participants needed
    36
  • sponsor
    University of Florida
Updated on 27 February 2022
arteriopathy
diabetes
anesthesia
hypertension
peripheral vascular disease
coronary artery disease
nerve block
chronic obstructive pulmonary disease
vascular disease
arterial disease

Summary

Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).

Description

Avoidance of general anesthesia in certain high-risk patient populations may have additional benefits beyond improved postoperative pain scores and analgesic consumption. The primary objective of this research will be to evaluate the ability of the femoral, sciatic, lateral femoral cutaneous nerve (LFCN), and obturator blocks to provide surgical anesthesia.

Details
Condition Peripheral Vascular Diseases, Hyperglycaemia (Diabetic), Hypertension, Coronary Artery Disease, Pulmonary Disease, Chronic Obstructive
Treatment peripheral Nerve block, Intravenous Sedatives, Lateral femoral cutaneous nerve blocks, Obturator nerve blocks
Clinical Study IdentifierNCT03404180
SponsorUniversity of Florida
Last Modified on27 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients undergoing above-the-knee amputation or knee disarticulation
Ability to understand and provide informed consent

Exclusion Criteria

Patient refusal or inability to provide informed consent
True allergy, not sensitivity, to any of the following substances
\- Local anesthetics
\- Propofol or other sedative agents
\- General anesthetic agents
Pregnancy
Severe hepatic impairment
Evidence of infection at or near the proposed needle insertion site
Any sensorimotor deficit, whether acute or chronic, as determined by the PI
Chronic use of opioid medication
BMI 35
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