Last updated on March 2018

One-stage Versus Two-stage Revision of the Infected Knee Arthroplasty


Brief description of study

This study investigates functional outcome and safety after one-stage versus two-stage revision of the infected knee arthroplasty.

Half of participants are treated with a one-stage surgical procedure, while the other half is treated with a two-stage procedure.

The investigators hypothesize that the functional outcome and quality of life of the participants is superior after one-stage surgery compared to two-stage surgery.

Detailed Study Description

A two-stage approach is the standard surgical procedure in the treatment of the chronically infected knee arthroplasty, but promising results have been reported after a one-stage approach from single-centre studies.

The potential benefits for the patients treated with a one-stage approach are many as they only have to go through surgery and rehabilitation once with shorter total length of hospital stay. However, no randomized controlled trials comparing outcome after the procedures have been performed so far.

Clinical Study Identifier: NCT03435679

Contact Investigators or Research Sites near you

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Jesper Fabrin, MD

K ge Hospital
Køge, Denmark
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Recruitment Status: Open


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