Last updated on March 2019

Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness-2

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Delirium | Shock | Critical Illness | Respiratory Failure
  • Age: Between 18 - 100 Years
  • Gender: Male or Female


  1. Adults 18 years old
  2. Admitted to a critical care unit requiring one or more of the following:

(a) Respiratory failure requiring invasive mechanical ventilation with an expected duration >24 hours (b) Shock of any etiology. Shock is defined by the need for one of the following vasopressors/inotropes: (i) Dopamine 7.5 mcg/kg/min (ii) Dobutamine 5 mcg/kg/min (iii) Norepinephrine 5 mcg/min (iv) Phenylephrine 75 mcg/min (v) Epinephrine at any dose (vi) Milrinone at any dose (if used in conjunction with another agent) (vii) Vasopressin 0.03 u/min(if used in conjunction with another agent)

  1. Admission to the ICU > 24 hours
  2. Life expectancy <24 hours
  3. Admitting diagnosis that affects the central nervous system
  4. Any reason that the subject may not be able to participate in the follow up assessments (i.e. limb amputation, paresis, neuromuscular disorders)

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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