Last updated on August 2019

Efficacy and Safety Study of BIIB074 in Participants With Small Fibre Neuropathy


Brief description of study

The primary objective of this study is to evaluate the efficacy of BIIB074 in treating pain experienced by participants with confirmed small fibre neuropathy (SFN) that is idiopathic or associated with diabetes mellitus. A secondary endpoint that relates to the primary objective is the change from Randomization to Week 12 of the double-blind period in mean average daily pain score.

The secondary objectives of this study are to evaluate the effect on worst pain, neuropathic pain quality, sleep interference due to pain, patient global impression, use of supplemental pain medication, and SFN symptoms in participants treated with BIIB074; to investigate the safety and tolerability of BIIB074 in participants with SFN; and to characterize the pharmacokinetics (PK) of BIIB074 in participants with SFN.

Clinical Study Identifier: NCT03339336

Find a site near you

Start Over

Research Site

Plovdiv, Bulgaria
  Connect »

Research Site

Greenfield Park, QC Canada
  Connect »

Research Site

Montreal, QC Canada
  Connect »

Research Site

St-Jerome, QC Canada
  Connect »

Research Site

Hradec Kralove, Czechia
  Connect »

Research site

Ostrava-Poruba, Czechia
  Connect »

Research Site

Pardubice, Czechia
  Connect »

Research Site

Copenhagen, Denmark
  Connect »

Research Site

Saint Priest En Jarez, France
  Connect »

Research Site

Corbeil-Essonnes, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Wurzburg, Germany
  Connect »

Research Site

Heraklion, Greece
  Connect »

Research Site

Thessaloniki, Greece
  Connect »

Research Site

Bekescsaba, Hungary
  Connect »

Research Site

Budapest, Hungary
  Connect »

Research Site

Kaposvar, Hungary
  Connect »

Research Site

Nyiregyhaza, Hungary
  Connect »

Research Site

Zalaegerszeg, Hungary
  Connect »

Research Site

Telese Terme, Italy
  Connect »

Research Site

Amsterdam, Netherlands
  Connect »

Research Site

Maastricht, Netherlands
  Connect »

Research Site

Bydgoszcz, Poland
  Connect »

Research Site

Oswiecim, Poland
  Connect »

Research Site

Warszawa, Poland
  Connect »

Research Site

Barcelona, Spain
  Connect »

Research Site

La Coruna, Spain
  Connect »

Research Site

Majadahonda, Spain
  Connect »

Kantonspital St. Gallen

St. Gallen, Switzerland
  Connect »

Research Site

Zurich, Switzerland
  Connect »

Research Site

Liverpool, United Kingdom
  Connect »

Research Site

London, United Kingdom
  Connect »

Research Site

Salford, United Kingdom
  Connect »

Research Site

Swansea, United Kingdom
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »

Research Site

Le Kremlin Bicêtre, France
  Connect »