Last updated on January 2019

Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis


Brief description of study

B7451015 is a Phase 3 study to evaluate PF-04965842 with or without Topical Medications in patients aged 12 years and older with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis and have completed a qualifying Phase 3 study. The efficacy and safety of two dosage strengths of PF-04965842, 100 mg and 200 mg taken orally once daily, will be evaluated over approximately two years of study participation. Patients who meet safety step-down criteria will have their dose reduced once, from 200 mg QD to 100 mg QD, or from 100 mg QD to placebo.

Clinical Study Identifier: NCT03422822

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California Dermatology & Clinical Research Institute
Encinitas, CA United States
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Tampa, FL United States
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NorthShore University HealthSystem Dermatology Clinical Trials Unit
Skokie, IL United States
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Dawes Fretzin Clinical Research Group, LLC
Indianapolis, IN United States
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Indianapolis, IN United States
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Norfolk, VA United States
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Savannah, GA United States
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Lynn Health Science Institute
Oklahoma City, OK United States
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Somerset Skin Centre
Troy, MI United States
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TCR Medical Corporation
San Diego, CA United States
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Maroubra, Australia
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Maroubra, Australia
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Upper Mount Gravatt, Australia
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Veracity Clinical Research Pty Ltd
Woolloongabba, Australia
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Skin and Cancer Foundation Inc
Carlton, Australia
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Carlton, Australia
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Baton Rouge, LA United States
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Health Concepts
Rapid City, SD United States
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Sinclair Dermatology
East Melbourne, Australia
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Richmond, Australia
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Santa Ana, CA United States
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Miami, FL United States
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Debrecen, Hungary
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Miskolc, Hungary
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Birmingham, AL United States
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Fort Worth, TX United States
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San Antonio, TX United States
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Lakewood, WA United States
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Montreal, QC Canada
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Largo, FL United States
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Fremont, CA United States
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Santa Monica, CA United States
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Coral Gables, FL United States
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Normal, IL United States
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Boca Raton, FL United States
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Houston, TX United States
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Calgary, AB Canada
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Vancouver, BC Canada
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Anaheim, CA United States
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Owensboro, KY United States
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Owensboro, KY United States
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Franklin, VA United States
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Norfolk, VA United States
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Ajax, ON Canada
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Rolling Hills Estates, CA United States
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Bellaire, TX United States
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Houston, TX United States
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Yangsan-si, Korea, Republic of
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Recruitment Status: Open


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