Last updated on February 2019

Phase 2 Study of TMX-049 in Subjects With Type 2 Diabetes and Albuminuria

Brief description of study

The primary objective of this study is to assess the effect of 2 dose levels of TMX-049 on urinary albumin excretion in subjects with Type 2 diabetes and albuminuria (a urinary albumin-to-creatinine ratio (UACR) 200 to 3000 mg/g and an estimated glomerular filtration rate (eGFR) 30 ml/min/1.73m2). Effects of each TMX-049 dose on UACR will be assessed in terms of ratios using log-transformed UACR at Baseline and after a 12-week period of treatment.

Clinical Study Identifier: NCT03449199

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Solaris Clinical Research, Llc

Meridian, ID United States

Carl R. Meisner Medical Clinic, PLLC

Sugar Land, TX United States

Valley Clinical Trials, Inc.

Northridge, CA United States

Endocrine Associates of Florida

Ocoee, FL United States


Flint, MI United States

Juno Research, LLC

Houston, TX United States

Manassas Clinical Research Center

Manassas, VA United States

San Marcus Research Clinic

Miami Lakes, FL United States

Leon Medical Research

Miami, FL United States

Cotton O'Neil Clinical Research Center

Topeka, KS United States

Rockwood Medical Clinic

Fort Worth, TX United States

Endocrine Associates

Houston, TX United States

Pioneer Research Solutions INC

Houston, TX United States

Diabetes Associates Medical Group

Orange, CA United States

East-West Medical Research Institute

Honolulu, HI United States

Associated in Endocrinology

Elgin, IL United States

Albany Medical College

Albany, NY United States

Carteret Medical Group

Morehead City, NC United States

University Diabetes & Endocrine Consultants

Chattanooga, TN United States

Aventiv Research- Phoenix

Mesa, AZ United States

Pines Care Research Center

Pembroke Pines, FL United States

Hanson Clinical Research Center

Port Charlotte, FL United States

Randolph Medical Associates

Asheboro, NC United States

Detweiler Family Medicine

Lansdale, PA United States

The Endocrine Center

Houston, TX United States

Bandera Family Health Clinic

San Antonio, TX United States

Desert Oasis Healthcare Medical Group

Palm Springs, CA United States

North America Research Institute

San Dimas, CA United States

Southeastern Clinical Research Institute

Augusta, GA United States

Community Clinical Research Center

Anderson, IN United States

Iowa Diabetes and Endocrinology Research

West Des Moines, IA United States

My Kidney Center

Manhattan, KS United States

Four Rivers Clincial Research

Paducah, KY United States

Biolab Research

Rockville, MD United States

Elite Research Center LLC

Flint, MI United States

Seacost Kidney & Hypertension

Portsmouth, NH United States

Wilmington Health

Wilmington, NC United States

Brookview Hills Research

Winston-Salem, NC United States

Knoxville Kidney Center

Knoxville, TN United States

The Medical Group of Texas

Fort Worth, TX United States

Houston Nephrology Research

Houston, TX United States

Comprehensive Research Institute

Alhambra, CA United States

Recruitment Status: Closed

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