Last updated on March 2018

Molecular PET/MR Imaging in Vivo Validation of Biomarker for Human Prostate Cancer


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Prostate Adenocarcinoma
  • Age: Between 40 - 85 Years
  • Gender: Male

Inclusion Criteria:

  • Males
  • 40-85 years of age
  • Patients with a biopsy-proven or clinically highly suspected prostate adenocarcinoma, or benign prostatic hyperplasia
  • Able to tolerate [11C]Choline PET scan and MRI scan
  • Written informed consent from the patient

Exclusion Criteria:

  • Acute prostatitis or non-urologic bacterial infection requiring medical treatment within the last 3 months.
  • History of AIDS in the period prior to the screening.3
  • Contraindications to [11C]Choline PET/MR scans
    1. Surgical implants including pacemaker implants, cochlear implants, dentures held in place by magnets imbedded in the gums and aneurysm clips except those inserted at CGMH
    2. Metallic prosthesis of the hip or pelvic region
    3. Renal function impairment with estimated glomerular filtration rate (eGFR) < 30 ml/min/1.73 m2
    4. Claustrophobia
    5. Medical drugs with choline
    6. Previous allergy to carbon-labeled radionuclide
  • Active other malignancy within the last 2 years
  • Subject which in the opinion of the investigator preclude participation for scientific reasons, for reasons of compliance, or for reasons of the subject's safety.
  • Prisoners or patients with mental illness

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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