Last updated on October 2018

Anesthesia for Pain After Ankle Fracture Surgery


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Ankle Fracture Surgery | Chronic Pain | Regional anesthesia
  • Age: Between 18 - 65 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Referred for surgery for open reduction and internal fixation for ankle fracture

Exclusion Criteria:

  • Unable to give informed consent in English
  • Unable to complete surveys in English
  • Unable to understand instructions for using pump in English
  • Unavailable for followup
  • Polytrauma; undergoing other surgeries or having other orthopedic injuries related to the precipitating cause of the ankle fracture
  • Infection
  • Peripheral vascular disease
  • Diabetes
  • Currently undergoing chemotherapy
  • Pregnancy
  • Currently lactating
  • Heart disease or heart rhythm disorder or taking anti-arrhythmic drugs
  • Severe renal impairment (Class 3 or worse kidney disease)
  • Liver disease (cirrhosis or liver failure)
  • Prior allergic reaction to any type of local anesthetic
  • Taking therapeutic doses of anti-coagulants or anti-platelet therapy (prophylactic doses started because of hospital admission are not an exclusion)
  • Currently taking antidepressants or other psychiatric medications
  • Single shot local nerve block prior to surgery was ineffective
  • Selected for neuraxial anesthesia rather than general anesthesia for the open reduction surgery
  • Already receiving chronic analgesic therapy for a separate chronic pain condition

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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